
Shift Your Hormones to Lose Weight!

đ Hello Friends,
Is there a magic pill or injection for weight loss?
In 2025, the popularity of injectable GLP-1 agonists has exploded. Originally designed for managing diabetes and obesity, these drugs are now being widely used by people trying to lose just 10â15 poundsâraising important questions about safety and long-term effects.
While GLP-1s can help suppress appetite, they can cause side effects. They increase insulin while slowing gut motility, often leading to nausea, constipation, and even small intestine bacterial overgrowth (SIBO). As a gut health doctor, Iâve seen a growing number of patients develop SIBO after starting weight loss injectionsâmaking GLP-1s a major new trigger for SIBO in 2025.
And when the injections stop? For many, the weight rebounds almost immediately. đ±
Itâs also important to understand that body composition matters far more than just the number on the scale. The goal is to lose fatânot muscle. Unfortunately, GLP-1s can cause you to lose both, including lean muscle and even facial fat, which can leave people looking gaunt or aged.
The good news: You can reset your metabolism and hunger hormones naturallyâwithout compromising your gut health or risking unpleasant side effects.
đ§ In my video on the Hormones that Control Your Weight, I explain how insulin, leptin, ghrelin, and cortisol influence your cravings, energy, and fat storageâand how you can restore balance through diet, lifestyle, and targeted supplements.
One of my favorite tools? Berberine Pro
Berberine activates AMPK, the same âmetabolic switchâ targeted by Metformin, improving insulin sensitivity and glucose metabolism. But Berberine goes far beyond blood sugarâitâs a powerful anti-inflammatory that calms the gut, supports the liver, lowers cholesterol, and fights off bad bacteria and yeast like Candida.
My formula also includes Alpha Lipoic Acid, a potent antioxidant that supports nerve health, brain function, and mitochondrial energy.
đ Unlike Metformin, Berberine doesnât contain synthetic fillers like PEGs, titanium dioxide, or dyesâand it wonât deplete your B12 levels.
Struggling with constant hunger or cravings?
Metabolism Support is a caffeine-free blend of green coffee bean extract, lemon verbena, and hibiscus polyphenols. Backed by randomized controlled trials, itâs been shown to reduce hunger, improve satiety, and lower waist circumferenceânaturally.
đœïž My top diet recommendation for sustainable weight loss is the Paleo Diet, often combined with intermittent fasting. Eliminating grains like bread, pasta, rice, cereal, and crackers helps reduce insulin spikes and curbs hunger. Many of my patients lose 15+ lbs in just a few months and feel more energizedâwith less appetite. Best of all, itâs far more sustainable than keto.
đâïž And donât forget movement!
Aim for 30â45 minutes of cardio daily, even in two short sessions. Add strength training 3x/week to build lean muscle and raise your resting metabolismâthis is key to long-term fat loss.
âš The bottom line: when you change your food, movement, and mindset, you change your hormones. Thatâs the real secret to losing weight, keeping it off, and feeling truly vibrant from the inside out.
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Howâs your diet and exercise routine going this year? Thereâs always room to grow! Focus on real, whole foods, prioritize protein, fiber, and healthy fats, and keep movingâwhether itâs walking, strength training, or yoga. Sustainable habits, not quick fixes, are the key to lasting energy, strength, and vitality. Wishing you great health!
Rajsree Nambudripad, MD |





