Shift Your Hormones to Lose Weight!
š Hello Friends,
Is there a magic pill or injection for weight loss?
In 2025, the popularity of injectable GLP-1 agonists has exploded. Originally designed for managing diabetes and obesity, these drugs are now being widely used by people trying to lose just 10ā15 poundsāraising important questions about safety and long-term effects.
While GLP-1s can help suppress appetite, they can cause side effects. They increase insulin whileĀ slowing gut motility, often leading to nausea, constipation, and evenĀ small intestine bacterial overgrowth (SIBO). As a gut health doctor, Iāve seen a growing number of patients develop SIBO after starting weight loss injectionsāmakingĀ GLP-1s a major new trigger for SIBO in 2025.
And when the injections stop? For many, the weight rebounds almost immediately. š±
Itās also important to understand thatĀ body compositionĀ matters far more than just the number on the scale. The goal is toĀ lose fatānot muscle.Ā Unfortunately, GLP-1s can cause you to lose both, including lean muscle and even facial fat, which can leave people looking gaunt or aged.
The good news: You can reset your metabolism and hunger hormonesĀ naturallyāwithout compromising your gut health or risking unpleasant side effects.
š§ In my video on theĀ Hormones that Control Your Weight, I explain how insulin, leptin, ghrelin, and cortisol influence your cravings, energy, and fat storageāand how you can restore balance through diet, lifestyle, and targeted supplements.
One of my favorite tools?Ā Berberine Pro
Berberine activatesĀ AMPK, the same āmetabolic switchā targeted by Metformin, improvingĀ insulin sensitivityĀ and glucose metabolism. But Berberine goes far beyond blood sugarāitās aĀ powerful anti-inflammatoryĀ that calms the gut, supports the liver, lowers cholesterol, and fights off bad bacteria and yeast likeĀ Candida.
My formula also includesĀ Alpha Lipoic Acid, a potent antioxidant that supports nerve health, brain function, and mitochondrial energy.
š Unlike Metformin, Berberine doesnāt contain synthetic fillers like PEGs, titanium dioxide, or dyesāand it wonāt deplete your B12 levels.
Struggling with constant hunger or cravings?
Metabolism SupportĀ is a caffeine-free blend of green coffee bean extract, lemon verbena, and hibiscus polyphenols. Backed by randomized controlled trials, itās been shown to reduce hunger, improve satiety, and lower waist circumferenceānaturally.
š½ļø My top diet recommendation for sustainable weight loss is theĀ Paleo Diet, often combined withĀ intermittent fasting. Eliminating grains like bread, pasta, rice, cereal, and crackers helps reduce insulin spikes and curbs hunger. Many of my patients lose 15+ lbs in just a few months and feel more energizedāwith less appetite. Best of all, itās far more sustainable than keto.
šāļø And donāt forget movement!
Aim forĀ 30ā45 minutes of cardio daily, even in two short sessions. AddĀ strength training 3x/weekĀ to build lean muscle and raise your resting metabolismāthis is key to long-term fat loss.
⨠The bottom line: when you change your food, movement, and mindset, you change your hormones. Thatās the real secret to losing weight, keeping it off, and feeling truly vibrant from the inside out.
Ā
Howās your diet and exercise routine going this year? Thereās always room to grow! Focus on real, whole foods, prioritize protein, fiber, and healthy fats, and keep movingāwhether itās walking, strength training, or yoga. Sustainable habits, not quick fixes, are the key to lasting energy, strength, and vitality. Wishing you great health! Rajsree Nambudripad, MD |